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In modern biochemical genetics,the flow of inherited information is from


A) protein \rightarrow RNA \rightarrow DNA.
B) DNA \rightarrow RNA \rightarrow protein.
C) DNA \rightarrow protein \rightarrow RNA.
D) RNA \rightarrow DNA \rightarrow protein.
E) RNA \rightarrow protein \rightarrow DNA.

F) D) and E)
G) A) and C)

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Tumor suppressor genes are


A) oncogenes that code for proteins that inhibit cell division.
B) anti-oncogenes that code for proteins that inhibit cell division.
C) oncogenes that code for proteins that stimulate cell division.
D) anti-oncogenes that code for proteins that stimulate cell division.
E) transposons that can be used as cancer therapy.

F) A) and E)
G) A) and D)

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Which of the following behaviors will NOT help prevent cancer?


A) avoid carcinogenic chemicals
B) avoid excessive sunlight
C) lower total fat intake
D) decrease intake of high-fiber foods
E) increase consumption of broccoli

F) C) and D)
G) A) and D)

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Hershey and Chase experimented with radioactively labeled phosphorus and sulfur to determine that DNA and not protein is the genetic material.Which of the following would NOT be an essential part of this experiment?


A) Sulfur is present in amino acids in the protein coat of bacteria.
B) Phosphorus is present in high amounts in DNA.
C) Sulfur is not present in DNA.
D) Phosphorus is not present in amino acids in the protein coat of bacteria.
E) DNA contains nitrogen.

F) B) and D)
G) A) and D)

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The hereditary material found in all cells is


A) DNA.
B) rRNA.
C) mRNA.
D) tRNA.
E) ATP.

F) All of the above
G) B) and C)

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Which part of an operon is incorrectly matched with its function?


A) promoter-where RNA polymerase first binds to DNA
B) regulator-binds to the repressor protein
C) structural-makes mRNA by transcription
D) operator-if unbound,allows RNA polymerase to bind to DNA
E) All of the answer choices are incorrectly matched with its function.

F) C) and E)
G) A) and E)

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In eukaryotes,control of gene expression is NOT by


A) translational control in cytoplasm after mRNA leaves the nucleus and before protein is produced.
B) transcriptional control in the nucleus based on which genes are transcribed and how fast they are transcribed.
C) posttranscriptional control in the nucleus after DNA is transcribed,including the speed with which mRNA leaves the nucleus.
D) posttranslational control in the cytoplasm that occurs after protein synthesis.
E) the use of repressor proteins and operators.

F) B) and D)
G) A) and E)

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Eukaryotic transcription factors assist the ______ in binding to the _________.


A) repressor; operator
B) RNA polymerase; promoter
C) DNA polymerase; promoter
D) helicases; operator
E) operator; repressor

F) B) and E)
G) A) and B)

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Which factor is likely to lead to a change in the genetic control of the individual and possibly cancer?


A) X-rays
B) ultraviolet radiation
C) cigarette smoke
D) pesticides
E) All of the answer choices can lead to cancer.

F) B) and D)
G) None of the above

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The X-ray diffraction photography of Rosalind Franklin and Maurice Wilkins was critical evidence


A) indicating that DNA has a double helix structure.
B) showing the bases of DNA were held together by hydrogen bonds.
C) showing equal numbers of purines and pyrimidines.
D) revealing the structure of the deoxyribose sugar.
E) of the location of each adenine,guanine,cytosine,and thymine.

F) B) and C)
G) A) and B)

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Which of the classes of RNA molecules carries the amino acids that are added to the growing polypeptide chain?


A) ribosomal RNA
B) transfer RNA
C) messenger RNA
D) primary mRNA transcript
E) ribozyme

F) A) and B)
G) C) and D)

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Messenger RNA is produced in the


A) cytoplasm.
B) ribosomes.
C) nucleus.
D) endoplasmic reticulum.
E) lysosome.

F) B) and E)
G) None of the above

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Which level of primary control in eukaryotic gene activity involves changes in the polypeptide chain before it becomes functional?


A) feedback control
B) translational control
C) transcriptional control
D) posttranscriptional control
E) posttranslational control

F) C) and D)
G) B) and E)

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Which level of primary control in eukaryotic gene activity involves the life span of the mRNA molecule and the ability of the mRNA to bind to ribosomes?


A) feedback control
B) translational control
C) transcriptional control
D) posttranscriptional control
E) posttranslational control

F) A) and E)
G) B) and D)

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In the Watson-Crick model of DNA,the "sides" of the ladder are composed of


A) sugars.
B) bases.
C) hydrogen bonds.
D) sugar-phosphate molecules.
E) phosphate groups.

F) A) and C)
G) A) and E)

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Which is NOT true about the genetic code?


A) It is exactly the same in all organisms.
B) It is composed of a triplet code of three bases per codon.
C) It produces 64 different possibilities of codon sequences.
D) Some amino acids are coded for by more than one codon.
E) It contains start and stop codons as instructions.

F) B) and D)
G) B) and C)

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____________ regulation occurs within a cell when the newly formed protein is modified.


A) Transcriptional
B) Posttranscriptional
C) Translational
D) Posttranslational
E) Operon

F) B) and C)
G) B) and D)

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Which of the following is NOT true of ribosomes?


A) They are produced in the nucleus of a eukaryotic cell.
B) They are made of RNA and proteins.
C) They are composed of two subunits that only come together when protein synthesis is about to occur.
D) They bind only one type of amino acid.
E) DNA serves as a template for rRNA.

F) B) and C)
G) C) and D)

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During the process of transcription,the information in


A) a protein is converted into RNA information.
B) RNA is converted into protein information.
C) RNA is converted into DNA information.
D) DNA is converted into RNA information.
E) DNA is converted into protein information.

F) All of the above
G) A) and E)

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Information from X-ray crystallographic data collected by _______ was used by Watson and Crick in their development of the model of DNA.


A) Chargaff
B) Griffith
C) McClintock
D) Franklin
E) Hershey and Chase

F) B) and E)
G) C) and D)

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