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DNA genetic coding and cell regulation is now understood to be incredibly important to every cell among organisms, and is also associated with viruses. Through the early and mid 1900s, scientists developed new molecular analysis methods that changed the foundations of how we understand "life" to function. Normal health and homeostasis, as well as disease, and natural variations in form and function among organisms are now better understood. Medical and biological applications have increased dramatically with the understanding of DNA molecule structure, and it is helpful to have recognition of the scientists and sequence of events contributing to our understanding. -The scientist (scientists) who discovered that bacteria can transfer genetic information is (are)


A) Chargaff.
B) Griffith.
C) Wilkins and Franklin.
D) Watson and Crick.
E) Hershey and Chase.

F) A) and E)
G) B) and C)

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DNA genetic coding and cell regulation is now understood to be incredibly important to every cell among organisms, and is also associated with viruses. Through the early and mid 1900s, scientists developed new molecular analysis methods that changed the foundations of how we understand "life" to function. Normal health and homeostasis, as well as disease, and natural variations in form and function among organisms are now better understood. Medical and biological applications have increased dramatically with the understanding of DNA molecule structure, and it is helpful to have recognition of the scientists and sequence of events contributing to our understanding. -The bacteria that Griffith experimented with were termed "R" and "S" bacteria because


A) of the way they grew on artificial media.
B) the R bacteria formed rough appearing colonies.
C) All of the answer choices are correct.
D) the S bacteria formed smooth appearing colonies.

E) B) and D)
F) B) and C)

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DNA genetic coding and cell regulation is now understood to be incredibly important to every cell among organisms, and is also associated with viruses. Through the early and mid 1900s, scientists developed new molecular analysis methods that changed the foundations of how we understand "life" to function. Normal health and homeostasis, as well as disease, and natural variations in form and function among organisms are now better understood. Medical and biological applications have increased dramatically with the understanding of DNA molecule structure, and it is helpful to have recognition of the scientists and sequence of events contributing to our understanding. -The twisted ladder shape of DNA is a result of the covalently bonded building blocks called


A) amino acids.
B) monosaccharides.
C) phospholipids.
D) sterols.
E) nucleotides.

F) A) and B)
G) C) and E)

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Based just on what is known about FOXP2,could Neandertals speak?


A) Yes, they have the same FOXP2 sequence as chimpanzees.
B) No, they have the same FOXP2 sequence as chimpanzees.
C) Yes, they have the same FOXP2 mutation as humans.
D) No, they have the same FOXP2 mutation as humans.
E) Yes, they have the same FOXP2 sequence as both humans and chimpanzees.

F) A) and B)
G) B) and E)

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A group of prokaryotic genes that are controlled together is a(n)


A) replication fork.
B) operon.
C) chromosome.
D) proteome.
E) ribosome.

F) D) and E)
G) B) and C)

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The Human Genome Project is a multinational project that reported complete identification of more than 20,000 genes in human DNA. Growing understanding has associated "normal" and naturally variable versions of the genes, producing specific proteins for human health and cell functions. Numerous mutated versions of the genes have been associated with particular human health problems and disease, due to the types of cells where mutations occur, the specific genes affected, and the type and extent of mutation. In these cases, the structure and function of proteins is ultimately impacted. Examine these examples to apply your knowledge of mutations to the descriptions provided. -Which of the following is not a common cause of mutation?


A) events of meiosis
B) exposure to chemical substances
C) exposure to radiation
D) errors in replication
E) obesity

F) A) and D)
G) D) and E)

Correct Answer

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The Human Genome Project is a multinational project that reported complete identification of more than 20,000 genes in human DNA. Growing understanding has associated "normal" and naturally variable versions of the genes, producing specific proteins for human health and cell functions. Numerous mutated versions of the genes have been associated with particular human health problems and disease, due to the types of cells where mutations occur, the specific genes affected, and the type and extent of mutation. In these cases, the structure and function of proteins is ultimately impacted. Examine these examples to apply your knowledge of mutations to the descriptions provided. -The COL1A1 gene in humans is responsible for producing collagens in healthy bone and cartilage.A mutation in COL1A1 is known to cause severe Osteogenesis Imperfecta,which is also known as "brittle bone disease," in which bones form irregularly and can break often,with even mild pressure and impacts.The mutation occurs as a "nonsense" mutation,dramatically shortening the proteins,occurring because the


A) codon that mutates causes a change in the amino acid specified.
B) codon that mutates does not cause a change in the amino acid specified.
C) mutation does not occur in a codon.
D) mutation is not in DNA.
E) codon that mutates causes a stop codon to occur instead of the placement of an amino acid.

F) D) and E)
G) A) and D)

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Figuer: Figuer:   -Using the genetic code shown here,predict what type of mutation has occurred in the hemoglobin sickle cell anemia allele. Normal allele 5'-GGAAUGAAACAGGAACCC-3' Mutant allele 5'-GGAAUGAAACAGGUACCC-3' A)  a point mutation, Glu to Val B)  a point mutation, Val to Glu C)  a frameshift mutation D)  addition of a new stop codon -Using the genetic code shown here,predict what type of mutation has occurred in the hemoglobin sickle cell anemia allele. Normal allele 5'-GGAAUGAAACAGGAACCC-3' Mutant allele 5'-GGAAUGAAACAGGUACCC-3'


A) a point mutation, Glu to Val
B) a point mutation, Val to Glu
C) a frameshift mutation
D) addition of a new stop codon

E) A) and B)
F) A) and C)

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DNA genetic coding and cell regulation is now understood to be incredibly important to every cell among organisms, and is also associated with viruses. Through the early and mid 1900s, scientists developed new molecular analysis methods that changed the foundations of how we understand "life" to function. Normal health and homeostasis, as well as disease, and natural variations in form and function among organisms are now better understood. Medical and biological applications have increased dramatically with the understanding of DNA molecule structure, and it is helpful to have recognition of the scientists and sequence of events contributing to our understanding. -The scientist (scientists) who used X-ray diffraction to help reveal the geometric structure of DNA is (are)


A) Wilkins and Franklin.
B) Avery and Macleod.
C) Watson and Crick.
D) Chargaff.
E) Hershey and Chase.

F) A) and C)
G) A) and E)

Correct Answer

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Which mutation in DNA would lead to the change of a single amino acid in a protein?


A) a missense mutation
B) a frameshift
C) a one base insertion
D) a nonsense mutation
E) a one base deletion

F) B) and E)
G) A) and B)

Correct Answer

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How can a single gene encode for more than one protein?


A) by transcribing multiple copies of mRNA
B) by using different codons
C) by mutating their genes
D) by removing different combinations of introns
E) by using transgenes

F) None of the above
G) A) and B)

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The process used by cells to convert the mRNA "message" into a sequence of amino acids is


A) mitosis.
B) replication.
C) amino acid synthesis.
D) transcription.
E) translation.

F) C) and E)
G) A) and B)

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In the bacterium E.coli,in the absence of lactose,a repressor protein binds to the operator region of the DNA,preventing the transcription of the genes of the lactose operon.

A) True
B) False

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In eukaryotic cells gene expression may be controlled by not allowing mRNA to leave the nucleus.

A) True
B) False

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In the Lac operon,the protein that binds to the operator to prevent transcription is


A) the promoter.
B) RNA polymerase.
C) the repressor.
D) lactose.
E) DNA polymerase.

F) A) and C)
G) C) and D)

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Figuer: Figuer:   -What type of mutation has occurred in the following? Normal allele 5'-GGAAUGAAACAGGAACCC-3' Mutant allele 5'-GGAAUGAAAUCAGGAACCC-3' A)  insertion of two bases B)  insertion of one base C)  deletion of two bases D)  deletion of one base E)  substitution -What type of mutation has occurred in the following? Normal allele 5'-GGAAUGAAACAGGAACCC-3' Mutant allele 5'-GGAAUGAAAUCAGGAACCC-3'


A) insertion of two bases
B) insertion of one base
C) deletion of two bases
D) deletion of one base
E) substitution

F) B) and C)
G) C) and E)

Correct Answer

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DNA genetic coding and cell regulation is now understood to be incredibly important to every cell among organisms, and is also associated with viruses. Through the early and mid 1900s, scientists developed new molecular analysis methods that changed the foundations of how we understand "life" to function. Normal health and homeostasis, as well as disease, and natural variations in form and function among organisms are now better understood. Medical and biological applications have increased dramatically with the understanding of DNA molecule structure, and it is helpful to have recognition of the scientists and sequence of events contributing to our understanding. -The scientist (scientists) who confirmed DNA was the genetic information by working with bacteria that infect viruses is (are)


A) Watson and Crick.
B) Avery and Macleod.
C) Griffith.
D) Hershey and Chase.
E) Chargaff.

F) A) and B)
G) All of the above

Correct Answer

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The observation that all races of humans have the same FOXP2 allele is evidence that ____ favored this allele.


A) random chance
B) artificial selection
C) independent assortment
D) natural selection
E) recombination

F) A) and C)
G) C) and D)

Correct Answer

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Because clindamycin and similar antibiotics bind to bacterial ribosomes,they work by inhibiting translation in the bacterial cells.

A) True
B) False

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Treating a solution from S strain Streptococcus pneumoniae with an enzyme that destroys ____ would prevent it from transforming type R bacteria into a form that would cause pneumonia in mice.


A) proteins or lipids
B) lipids
C) DNA or proteins
D) DNA
E) proteins

F) B) and C)
G) B) and E)

Correct Answer

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