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A/an _____ is the protein shell around the nucleic acid core of a virus.


A) capsomere
B) capsid
C) spike
D) envelope
E) monolayer

F) A) and E)
G) C) and E)

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Viruses ______.


A) cannot be seen in a light microscope
B) are prokaryotic
C) contain 70S ribosomes
D) undergo binary fission

E) None of the above
F) A) and D)

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When a bacterium acquires a trait from its temperate phage,it is called ______.


A) transformation
B) lysogenic conversion
C) viral persistence
D) transcription
E) translation

F) B) and D)
G) A) and E)

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Which of the following represents a virus family name?


A) Herpes simplex virus
B) Herpesviridae
C) Picornavirus
D) Enterovirus
E) Hepatitis B virus

F) A) and B)
G) A) and C)

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Viruses are simple,noncellular,and lack mRNA.

A) True
B) False

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Infectious protein particles are called ______.


A) viroids
B) phages
C) prions
D) oncogenic viruses
E) spikes

F) C) and E)
G) A) and C)

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A treatment for bacterial infections from the early 20th century has made a comeback; the use of bacterial viruses to eliminate bacterial infections.Which explanation most accurately describes the mechanism of action behind this treatment?


A) A wide variety of bacteria cause a large percentage of human infections, producing much sickness and death.
B) Viruses can infect bacteria, transferring pathogenic genes. The viral genes can then be suppressed, causing the bacteria to not replicate viruses.
C) The attachment structures on the virus and the receptors on the host cells make for exquisite specificity of viruses for particular bacterial species.
D) Antibiotic resistance in humans is on the increase, so using a different kind of therapy is more beneficial.

E) A) and B)
F) All of the above

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In general,most DNA viruses multiply in the host cell's _____,while most RNA viruses multiply in the host cell's _____.


A) nucleus; cytoplasm
B) cytoplasm; cell membrane
C) cell membrane; cytoplasm
D) cytoplasm; nucleus
E) nucleus; endoplasmic reticulum

F) A) and C)
G) B) and D)

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New,nonenveloped virus release occurs by ______.


A) lysis
B) budding
C) exocytosis
D) both lysis and budding
E) both budding and exocytosis

F) A) and B)
G) A) and C)

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Viruses with _____-sense RNA contain the correct message for translation,while viruses with _____-sense RNA must first be converted into a correct message.


A) positive; negative
B) negative; positive
C) primary; secondary
D) secondary; primary
E) intermediate; primary

F) A) and B)
G) A) and C)

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Viral growth in bird embryos can cause discrete,opaque spots in the embryonic membranes called ______.


A) patches
B) buds
C) plaques
D) cytopathic effects
E) pocks

F) B) and C)
G) A) and C)

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Why do some animal viruses have an external envelope,while bacteriophages never do?


A) Some animal viruses bud out, taking part of the plasma membrane with them, whereas phages always lyse the host bacterial cell when they exit.
B) When bacteriophages bud out, the plasma membrane is beneath the cell wall and therefore cannot be removed.
C) When animal cells are lysed, part of the plasma membrane attaches to the virus; in bacterial cells, it is covered by the cell wall.
D) When phages bud out of the host bacterial cell, they take with them part of the cell wall which forms the capsid, not an envelope.

E) B) and C)
F) A) and B)

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You are working in a laboratory that is studying a newly isolated virus.Your job is to culture the virus using in vitro methods.Upon observing your inoculated tissue culture specimen one day,you notice clumps of cells growing on top of the original monolayer of cells.Microscopic analysis of stained cells from the culture reveal an alteration in host cell membrane protein content and chromosomal structure.Based upon this information,you hypothesize that the virus you are studying is ______.


A) a bacteriophage
B) a prion
C) a viroid
D) an oncovirus
E) a satellite virus

F) A) and E)
G) D) and E)

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Viruses are not filterable.

A) True
B) False

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Two noncellular agents,smaller than viruses,are infectious proteins called _____ and infectious RNA strands called _____.


A) prions; capsomeres
B) virions; prions
C) viroids; phages
D) prions; phages
E) prions; viroids

F) C) and E)
G) B) and D)

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In order to synthesize proteins,a virus with a genome comprised of single-stranded negative-sense RNA


A) can directly translate its negative-sense RNA strand into proteins.
B) must use reverse transcriptase to make a negative-sense DNA strand first.
C) must use DNA polymerase to make a positive-sense DNA strand first.
D) must use its negative-sense strand as a template to make a positive-sense RNA.

E) A) and C)
F) A) and B)

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Which of the following is not a characteristic of a transformed cell?


A) Viral nucleic acid integrated into host DNA
B) Decreased growth rate
C) Alterations in chromosomes
D) Changes in cell surface molecules
E) Capacity to divide indefinitely

F) None of the above
G) All of the above

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Select the statement that most accurately describes the action of antimicrobial drugs today.


A) Antiviral drug treatment is more effective than vaccination against a viral disease.
B) Effective antiviral drugs have a long history of development and use.
C) Antiviral drugs often result in toxic side effects due to their inhibition of host cell activity.
D) The development of antiviral drug resistance has not been observed, as compared to the high rate of antibiotic resistance seen today.

E) None of the above
F) B) and C)

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Viruses are considered ultramicroscopic because they range in size from 2 mm to 450 mm.

A) True
B) False

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Uncoating of viral nucleic acid


A) does not occur in bacteriophage multiplication.
B) involves enzymatic destruction of the capsid.
C) occurs during penetration in the multiplication cycle.
D) occurs before replication.
E) All of the choices are correct.

F) B) and C)
G) A) and C)

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