Question 1

Sulfa drugs work on

Accepted Answer

A)  nucleic acid biosynthesis.
B)  ribosome biosynthesis.
C)  peptidoglycan biosynthesis.
D)  folic acid biosynthesis.E) A) and C)
F) All of the above

Question 2

An antimicrobial with a low therapeutic index is a safer choice compared to a drug with a high therapeutic index.

Accepted Answer

A) True 
 B)False

Question 3

Which of the following is not used to treat malaria?

Accepted Answer

A)  Quinine
B)  Chloroquine
C)  Metronidazole
D)  Primaquine
E)  MeflaquineF) A) and D)
G) C) and E)

Question 4

Aminoglycosides

Accepted Answer

A)  destroy peptidoglycan.
B)  are metabolic analogs of PABA and block folic acid synthesis.
C)  attach to the 30S ribosomal subunit and disrupt protein synthesis.
D)  damage cell membranes.
E)  block peptidases that cross-link glycan molecules.F) A) and B)
G) D) and E)

Question 5

Which of the following blocks HIV binding to host cell receptors?

Accepted Answer

A)  AZT
B)  Acyclovir
C)  Nevirapine
D)  Fuzeon
E)  AmantidineF) A) and D)
G) B) and E)

Question 6

Antibiotics that disrupt bacterial ribosomes can also affect

Accepted Answer

A)  eukaryotic large ribosomal subunit.
B)  eukaryotic small ribosomal subunit.
C)  ribosomal RNA.
D)  eukaryotic mitochondrial ribosomes.E) All of the above
F) C) and D)

Question 7

Species of Bacillus produce bacitracin and the polymyxin drugs.

Accepted Answer

A) True 
 B)False

Question 8

The first modern antimicrobial drugs were sulfa drugs.

Accepted Answer

A) True 
 B)False

Question 9

An antiviral that is a guanine analog would have an antiviral mode of action that

Accepted Answer

A)  blocks penetration.
B)  blocks transcription and translation.
C)  inhibits DNA synthesis.
D)  blocks maturation.
E)  bonds to ergosterol in the cell membrane.F) A) and E)
G) B) and D)

Question 10

Sulfonamides

Accepted Answer

A)  interfere with elongation of peptidoglycan.
B)  are metabolic analogs of PABA and block folic acid synthesis.
C)  attach to the 30S ribosomal subunit and disrupt protein synthesis.
D)  damage cell membranes.
E)  block peptidases that cross-link glycan molecules.F) B) and E)
G) C) and E)

Question 11

Broad-spectrum drugs that disrupt the body's normal biota often cause ______.

Accepted Answer

A)  nephrotoxicity
B)  superinfections
C)  allergic reactions
D)  drug toxicityE) All of the above
F) A) and D)

Question 12

The drug used against intestinal anaerobic bacteria, that can also alter normal biota leading to antibiotic-associated colitis, is ______.

Accepted Answer

A)  chloramphenicol
B)  clindamycin
C)  ciprofloxacin
D)  bacitracin
E)  gentamicinF) A) and B)
G) A) and C)

Question 13

Drugs that act by mimicking the normal substrate of an enzyme, thereby blocking its active site, are called ______.

Accepted Answer

A)  inhibitors
B)  blockers
C)  competitive inhibitors
D)  noncompetitive inhibitorsE) A) and B)
F) B) and C)

Question 14

All of the following pertain to fluoroquinolones, except

Accepted Answer

A)  they are broad spectrum.
B)  they include ciprofloxacin and levofloxacin.
C)  they are nephrotoxic.
D)  they are used to treat respiratory, urinary, and sexually transmitted infections.
E)  they are readily absorbed from intestines.F) A) and B)
G) C) and D)

Question 15

There are fewer antifungal, antiprotozoan, and antihelminthic drugs compared to antibacterial drugs because fungi, protozoa, and helminths

Accepted Answer

A)  do not cause many human infections.
B)  are not affected by antimicrobials.
C)  are so similar to human cells that drug selective toxicity is difficult to achieve.
D)  are parasites found inside human cells.
E)  have fewer target sites in their cells compared to bacteria.F) B) and C)
G) C) and D)

Question 16

Each of the following affect cell walls, except ______.

Accepted Answer

A)  penicillin
B)  cycloserine
C)  vancomycin
D)  erythromycin
E)  cephalosporinF) A) and E)
G) C) and D)

Question 17

Who is considered to be the father of modern antibiotics?

Accepted Answer

A)  Domagk
B)  Crick
C)  Fleming
D)  Chargaff
E)  WatsonF) A) and B)
G) C) and D)

Question 18

If pathogen A is more resistant to an erythromycin disc on a Kirby-Bauer plate compared to pathogen B, then pathogen A will have a/n _____ zone of inhibition compared to pathogen B.

Accepted Answer

A)  	smaller
B)  	equal
C)  	largerD) A) and C)
E) B) and C)

Question 19

Nutrients that encourage the growth of beneficial microbes in the intestines are known as ______.

Accepted Answer

A)  prebiotics
B)  probiotics
C)  lantibiotics
D)  phytobiotics
E)  riboswitchesF) None of the above
G) B) and D)

Question 20

Bacteria can have a natural resistance to a drug to which they have never been exposed.

Accepted Answer

A) True 
 B)False

Exam 12: Antimicrobial Treatment

An antiviral that is a guanine analog would have an antiviral mode of action that

Correct AnswerverifiedShow Answer

Each of the following affect cell walls, except ______.

Correct AnswerverifiedShow Answer

All of the following pertain to fluoroquinolones, except

Correct AnswerverifiedShow Answer

An antimicrobial with a low therapeutic index is a safer choice compared to a drug with a high therapeutic index.

Correct AnswerverifiedShow Answer

Species of Bacillus produce bacitracin and the polymyxin drugs.

Correct AnswerverifiedShow Answer

Broad-spectrum drugs that disrupt the body's normal biota often cause ______.

Correct AnswerverifiedShow Answer

Sulfa drugs work on

Correct AnswerverifiedShow Answer

Sulfonamides

Correct AnswerverifiedShow Answer

Drugs that act by mimicking the normal substrate of an enzyme, thereby blocking its active site, are called ______.

Correct AnswerverifiedShow Answer

If pathogen A is more resistant to an erythromycin disc on a Kirby-Bauer plate compared to pathogen B, then pathogen A will have a/n _____ zone of inhibition compared to pathogen B.

Correct AnswerverifiedShow Answer

The drug used against intestinal anaerobic bacteria, that can also alter normal biota leading to antibiotic-associated colitis, is ______.

Correct AnswerverifiedShow Answer

The first modern antimicrobial drugs were sulfa drugs.

Correct AnswerverifiedShow Answer

Which of the following is not used to treat malaria?

Correct AnswerverifiedShow Answer

Aminoglycosides

Correct AnswerverifiedShow Answer

Who is considered to be the father of modern antibiotics?

Correct AnswerverifiedShow Answer

Bacteria can have a natural resistance to a drug to which they have never been exposed.

Correct AnswerverifiedShow Answer

Antibiotics that disrupt bacterial ribosomes can also affect

Correct AnswerverifiedShow Answer

There are fewer antifungal, antiprotozoan, and antihelminthic drugs compared to antibacterial drugs because fungi, protozoa, and helminths

Correct AnswerverifiedShow Answer

Which of the following blocks HIV binding to host cell receptors?

Correct AnswerverifiedShow Answer

Nutrients that encourage the growth of beneficial microbes in the intestines are known as ______.

Correct AnswerverifiedShow Answer

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