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Place the following in order from skull to brain: 1) subarachnoid space; 2) arachnoid mater; 3) dura mater; 4) pia mater.


A) Subarachnoid space, arachnoid mater, dura mater, pia mater
B) Dura mater, arachnoid mater, subarachnoid space, pia mater
C) Dura mater, arachnoid mater, pia mater, subarachnoid space
D) Arachnoid mater, subarachnoid space, dura mater, pia mater
E) Pia mater, arachnoid mater, subarachnoid space, dura mater

F) A) and E)
G) C) and D)

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The RN updates the patient's son on the plan of treatment. What is the most appropriate antibiotic to treat this illness?


A) Vanomycin
B) Cefotaxime
C) Acyclovir
D) No antibiotic therapy is indicated.

E) None of the above
F) A) and B)

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Subacute sclerosing panencephalitis is caused by a prion.

A) True
B) False

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A lumbar puncture is performed, which confirms a diagnosis of meningitis. The pathology report indicates that the cerebral spinal fluid sample was found to have gram-positive cocci in pairs and the patient is diagnosed with pneumococcus. What is the causative organism?


A) Streptococcus pneumoniae
B) Neisseria meningitides
C) Haemophilus influenzae
D) Listeria monocytogenes

E) B) and C)
F) None of the above

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A

Which of the following is not true of meningoencephalitis?


A) Causative organisms are Naegleria fowleri and Acanthamoeba
B) Infections of both the brain and meninges
C) Causative organisms are viruses
D) Modes of transmission are direct contact and swimming in warm fresh water
E) Treatment for primary amoebic meningoencephalitis is mostly ineffective

F) B) and D)
G) D) and E)

Correct Answer

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C

Treatment of an animal bite for possible rabies includes ________.


A) debridement
B) washing bite with soap or detergent
C) infusing the wound with human rabies immune globulin (HRIG)
D) postexposure vaccination with inactive vaccine
E) All of the choices are correct.

F) A) and E)
G) A) and D)

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The best defense against arboviruses is ________.


A) prophylactic rifampin
B) vector control
C) vaccination
D) prompt treatment with acyclovir
E) All of the choices are correct.

F) B) and D)
G) B) and E)

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Which is incorrect about rabies?


A) Is a zoonotic disease
B) Wild populations of bats, skunks, raccoons, cats, and canines are primary reservoirs
C) Transmission can involve bites, scratches, and inhalation
D) Average incubation in human is 1 week
E) Symptoms include anxiety, agitation, muscle spasms, convulsions, and paralysis

F) None of the above
G) B) and C)

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Agricultural workers and field archaeologists are exposed to this organism, which, although entering via the respiratory tract, can cause meningitis.


A) Haemophilus influenzae
B) Coccidioides immitis
C) Cryptococcus neoformans
D) Streptococcus pneumoniae
E) Neisseria meningitidis

F) A) and E)
G) B) and C)

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Tetanus differs from botulism in that ________.


A) tetanus results in flaccid paralysis while botulism paralysis is rigid
B) tetanus results from an exotoxin; botulism results from an endotoxin
C) there is a vaccine for botulism, but not for tetanus
D) muscles cannot relax in tetanus; muscles cannot contract in botulism
E) All of the choices are correct.

F) A) and D)
G) B) and D)

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Which organism is the definitive host for Toxoplasma gondii?3


A) Cat
B) Dog
C) Mouse
D) Mosquito
E) Raccoon

F) A) and D)
G) B) and C)

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A

Spongiform encephalopathies are ________.


A) associated with abnormal, transmissible protein in the brain
B) chronic, fatal infections of the nervous system
C) caused by prions
D) Creutzfeldt-Jakob disease, kuru, and Gerstmann-Straussler-Scheinker syndrome
E) All of the choices are correct.

F) A) and B)
G) A) and C)

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Prions can be destroyed by autoclaving.

A) True
B) False

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In an effort to limit transmission of the Zika virus, scientists have genetically modified the Aedes mosquito. Evaluate the statements below and determine which describes the most plausible method to minimize disease.


A) Male Aedes mosquitoes are genetically modified to have a "lethality" gene. They are raised in the lab being fed with the antidote tetracycline. Once released into the wild, they mate with females and the offspring, without access to tetracycline, die before reproducing.
B) Male Aedes mosquitoes are genetically modified to contain a gene that codes for a bacterial toxin. Once released into the wild they die before they are able to mate with females.
C) Male Aedes mosquitoes are genetically modified to be temperature-sensitive mutants. They are raised in the lab with air-conditioning, but once released into the wild, the heat and humidity in tropical climates causes their enzymes to denature, killing them before they can reproduce.
D) Male Aedes mosquitoes are genetically modified to produce a protein that mimics the action of DEET in insect repellants. The males mate with females and during the mating they pass the protein to the female and both mosquitoes are killed in the process.

E) None of the above
F) B) and C)

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The foodborne disease that involves neurotoxin is ________.


A) gastrointestinal anthrax
B) bacillus cereus intoxication
C) botulism
D) clostridium perfringens gastroenteritis
E) All of the choices are correct.

F) All of the above
G) D) and E)

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The organism responsible for the majority of neonatal meningitis is ________.


A) Streptococcus agalactiae
B) Escherichia coli K1
C) Listeria monocytogenes
D) Haemophilus influenzae
E) Neisseria meningitidis

F) B) and E)
G) A) and B)

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Cryptococcal meningitis is highly communicable among humans.

A) True
B) False

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Subacute encephalitis may be caused by ________.


A) Toxoplasma gondii
B) prions
C) herpes simplex virus
D) persistent measles virus
E) All of the choices are correct.

F) B) and E)
G) A) and B)

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Which of the following has the highest mortality rate?


A) Western equine encephalitis
B) St. Louis encephalitis
C) California encephalitis
D) Eastern equine encephalitis
E) West Nile encephalitis

F) B) and D)
G) A) and C)

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Which of the following is not a prion disease?


A) Scrapie
B) Creutzfeldt-Jakob disease
C) Bovine spongiform encephalopathy
D) Subacute sclerosing panencephalitis
E) All of the choices are prion diseases.

F) A) and E)
G) A) and D)

Correct Answer

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